Possible chromosomal and germline integration of human herpesvirus 7
نویسندگان
چکیده
منابع مشابه
Chromosomal integration of human herpesvirus 6 is the major mode of congenital human herpesvirus 6 infection.
OBJECTIVE We examined the frequency and characteristics of chromosomally integrated human herpesvirus 6 among congenitally infected children. METHODS Infants with and without congenital human herpesvirus 6 infection were prospectively monitored. Cord blood mononuclear cell, peripheral blood mononuclear cell, saliva, urine, and hair follicle samples were examined for human herpesvirus 6 DNA. H...
متن کاملMolecular biology and clinical associations of Roseoloviruses human herpesvirus 6 and human herpesvirus 7.
Human herpesvirus 6 (HHV-6) and human herpesvirus 7 (HHV-7) are members of the Roseolovirus genus within the Betaherpesvirinae subfamily. HHV-6 and HHV-7 primary infection occurs in early childhood and causes short febrile diseases, sometimes associated with cutaneous rash (exanthem subitum). Both HHV-6 and HHV-7 are highly prevalent in the healthy population, establish latency in macrophages a...
متن کاملAssociation of pityriasis rosea with human herpesvirus-6 and human herpesvirus-7 in Taipei.
BACKGROUND AND PURPOSE Pityriasis rosea (PR) is a common papulosquamous skin disease with unknown etiology. The possible relationship of PR with human herpesvirus infection (HHV) has been extensively studied. This study used the polymerase chain reaction (PCR) to investigate the presence of human herpesvirus 6 and 7 (HHV-6 and HHV-7) in 41 PR patients from two hospitals in Northern Taiwan. The ...
متن کاملCytomegalovirus, human herpesvirus-6, and human herpesvirus-7 in hematological patients.
The prototype member of the Betaherpesvirinae subfamily, cytomegalovirus (CMV), is the most important infectious pathogen in transplant recipients, including those receiving bone marrow or stem cell grafts. Overt CMV disease such as pneumonitis is notoriously difficult to treat. Antiviral prophylaxis, rapid diagnostic tests to identify CMV infection, and preemptive antiviral chemotherapy are si...
متن کاملLatency, Integration, and Reactivation of Human Herpesvirus-6
Human herpesvirus-6A (HHV-6A) and human herpesvirus-6B (HHV-6B) are two closely related viruses that infect T-cells. Both HHV-6A and HHV-6B possess telomere-like repeats at the terminal regions of their genomes that facilitate latency by integration into the host telomeres, rather than by episome formation. In about 1% of the human population, human herpes virus-6 (HHV-6) integration into germl...
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ژورنال
عنوان ژورنال: Journal of General Virology
سال: 2017
ISSN: 0022-1317,1465-2099
DOI: 10.1099/jgv.0.000692